NCT01461902已完成不适用
Measuring Vasospasm, Biomarkers, and Neurocognitive Outcomes in Pediatric Traumatic Brain Injury
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 6
- 试验地点
- 1
- 主要终点
- Vasospasm detection by Transcranial Doppler Ultrasound
研究概览
简要总结
The purpose of this study is to assess for vasospasm using Transcranial Doppler (TCD) and brain injury biomarkers, and evaluate neurocognitive outcome data in pediatric traumatic brain injury (TBI) patients who have experienced a mild to severe head injury.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 5 Days 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •admission to Duke University Children's Hospital;
- •age 5 days to 15 years;
- •a diagnosis of a TBI with a GCS 3-15;
- •capable of adequate TCD ultrasound examination;
- •and presence of intravenous or arterial access (blood) and/or an EVD for cerebrospinal fluid (CSF) and/or Foley catheter/ability to void unassisted (urine) biomarker collection unless they are excluded based on the exclusion criteria.
排除标准
- •the presence of previously diagnosed significant neurodevelopmental delay,
- •a diagnosis of non-traumatic intracranial hemorrhage and
- •parents/legal guardians who do not speak or understand English.
结局指标
主要结局
Vasospasm detection by Transcranial Doppler Ultrasound
时间窗: 8 days
Daily transcranial doppler ultrasound performed in pediatric traumatic head injury patients.
次要结局
- Detection of biomarkers in pediatric traumatic brain injury(2 days)
研究者
研究点 (1)
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