CTRI/2022/11/047156招募中未知
Efficacy of propranolol in tremors in patients with Spinocerebellar Ataxia 12: A single centre double blind randomized placebo controlled pilot trial
AIIMS New Delhi0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •All genetically proven SCA 12 patients with tremors.
- •Age 18 yrs to 60 years.
- •Tremor severity score of at least 2 in at least one upper extremity on at least one of the three manoeuvres on the TETRAS scale.
排除标准
- •1.Patients with conditions that are absolute or relative contraindications to the use of beta blockers-
- •a. Bronchial asthma, COPD
- •b. Peripheral vascular disease
- •c. Diabetes Mellitus
- •d. Acute Heart failure
- •e. heart block
- •f. bradycardia with heart rate less than 60 bpm
- •blood pressure less than 90 mm Hg systolic and 60 mm Hg diastolic.
- •2. All other possible causes of tremors
- •a. Hyperthyroidism
- •b. Parkinsonism
- •c.drugs like beta agonists ,theophylline, valproate, lamotrigine
- •3.Not giving consent
- •4.Pregnancy and lactation
研究者
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