Effect of Nitya Virechana with Narayana Churna in the Management of Non-Alcoholic Fatty Liver Disease (NAFLD)
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Change in the grade
研究概览
简要总结
This trial is conducted to assess the Effect of Nitya Virechana with Narayana Churna in the Management of Non alcoholic Fatty Liver Disease. During the intervention the participants will be given 12 g Narayana Churna with hot water at bed time for a period of 30 days as Nitya Virechana.The study will be conducted in Government Ayurveda College Hospital, Tripunithura having laboratory and USG facility which makes the study more feasible .The study design is pre and post- study .A sample of 28 will be selected based on inclusion and exclusion criteria.The subjects will be administered Narayana churna for the first 10 days on IP basis and the remaining duration on OP basis. The assessment of Virechana will be done daily basis.They will be subjected to detailed clinical evaluation and investigation including USG Abdomen, LFT, Lipid profile ,Platelet, Electrolyte, RFT and FBS. Fibrosis score will also be calculated .Elastography will be done for a sub group. USG and Elastography will be done before and after the treatment. All the above blood tests will be checked on 10 th, 20 th ,30 th and 60 th day. Data collection will be done through case proforma,USG abdomen , blood tests and elastography in a sub group.Data collected will be statically analysed through appropriate tests and conclusion will be drawn.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 55.00 Year(s)(—)
- 性别
- All
入选标准
- •Subject among age group 30-55 who are diagnosed as fatty liver Grade 1and 2, diagnosed by USG and Fibroscan in a sub group at the OPD and IPD of Govt.
- •Ayurveda College Hospital ,Tripunithura.
排除标准
- •1.Known cases of Major Systemic illness 2.Known cases of Malignancy 3.Known cases of Portal hypertension 4.Known cases of Splenomegaly 5.Pregnant and lactating women 6.Subjects having Mridu koshta.
结局指标
主要结局
Change in the grade
时间窗: 30 days
of fatty liver as observed through USG Abdomen
时间窗: 30 days
次要结局
- 1. Change in the score(of NAFLD fibrosis score)
研究者
DrSheejaS
Govt Ayurveda College Hospital,Tripunithura
