NL-OMON29543招募中不适用
Observational study;<br>Combined pan-chromoendoscopy and confocal endomicroscopy for the diagnosis of colorectal neoplasia in subjects at high-risk for colorectal cancer.
Dr. S. Sanduleanu, gastroenterologistUniversity Hospital MaastrichtDepartment of Gastroenterology and HepatologyPO BOX 5800, 6202 AZMaastrichte-mail: sda@sint.azm.nltel: 0031-43-38750210 个研究点目标入组 60 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 60
研究概览
简要总结
- Confocal laser endomicroscopy: technical status and current indications. Endoscopy 2006;38(12):1275-83. Hoffman, A., Goetz, M., Vieth, M., Galle, P.R., Neurath, M.F., Kiesslich, R;
2. Confocal laser endoscopy for diagnosing intraepithelial neoplasias and colorectal cancer in vivo. Gastroenterology 2004;127(3):706-13. Kiesslich, R., Burg, J., Vieth, M., Gnaendiger, J., Enders, M., Delaney, P., Polglase, A., McLaren, W., Janell, D., Thomas, S., Nafe, B., Galle, P.R., Neurath, M.F;
3. The role of high-magnification-chromoscopic colonoscopy in hereditary nonpolyposis colorectal cancer screening: a prospective “back-to-back” endoscopic study.
Am J Gastroenterol 2005; 100:2167-73 Hurlstone, D.P., Karajeh, M., Cross, S.S., McAlindon, M.E., Brown, S., Hunter, M.D., Sanders, D.S.
cancer in vivo.
Gastroenterology 2004;127(3):706-13. Kiesslich, R., Burg, J., Vieth, M., Gnaendiger, J., Enders, M., Delaney, P., Polglase, A., McLaren, W., Janell, D., Thomas, S., Nafe, B., Galle, P.R., Neurath, M.F.
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •1. Clinical diagnostic criteria for either HNPCC (Amsterdam II criteria , Bethesda criteria or genetic criteria) or familial colorectal cancer type X – (1) CRC diagnosed age < 50 years;
- •2. at least 2 first-degree relatives with CRC regardless of age;
排除标准
- •1. Age < 18 years, presence of inflammatory bowel disease, or known polyposis syndromes;
- •2. Patients with incomplete endoscopic procedure due to anatomic or technique-related factors.
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