Cross-cultural Adaptation of Peripheral Artery Disease Quality of Life Questionnaire (PADQOL)into Indian Nepali Language

Peripheral artery disease (PAD) is a condition where arteries that carry blood from the heart to the limbs become narrowed due to plaque buildup. This narrowing, known as stenosis, restricts blood flow, leading to symptoms like leg pain during physical activity, known as claudication. If left untreated, PAD can progress to more severe symptoms, such as pain at rest, non-healing wounds, and even limb amputation. It also increases the risk of heart attacks and strokes.

Risk factors for PAD include smoking, diabetes, high blood pressure, high cholesterol, and aging. Studies in India have shown varying prevalence rates, with Kerala and Sikkim reporting significant numbers of cases, often associated with high cholesterol, hypertension, diabetes, and smoking.

To better understand how PAD affects quality of life in the Indian Nepali population, The Peripheral Artery Disease Quality of Life (PADQOL) Questionnaire was translated and cross culturally adapted by using Beaton’s guideline. To determine validity and reliability of the questionnaire PADQOL, it will be applied on 192 patients with Peripheral Artery Disease meeting the eligibility criteria and after a wash out period of 24 hrs it will be applied again on the same patients along with SF 36. after the completion of the procedure data will be analyzed by using SPP version 27.

The translated questionnaire provides healthcare providers with a culturally sensitive tool to assess and address the impact of PAD on patients’ lives, ultimately improving care and outcomes for the Indian Nepali community affected by this condition.