Studying Pleuroscopy in Routine Pleural Infection Treatment Trial

Southmead Hospital0 个研究点目标入组 12 人开始时间: 2017年7月3日最近更新: 2022年9月5日

适应症

试验速览

暂无简介。

•1. Pleural effusion due primarily to suspected pleural infection requiring chest tube drainage, defined as an effusion, in the appropriate clinical context, with one or more of the following characteristics:
•1.1. Fluid pH =7.20 or visually contains pus
•1.2. Pleural fluid glucose =3.4 mmol/L
•1.3. Positive bacterial or mycobacterial culture
•1.4. Positive gram stain or stain for acid-fast bacilli
•2. Clinical team are able to perform a medical thoracoscopy, if allocated, on either the same or the next day as the effusion is diagnosed as requiring drainage
•3. Clinical team are able to deliver the post-procedure trial schedule as detailed in the protocol
•4. Patient is willing to consider trial entry and receive information sheet

•1. Any contraindication, in the opinion of the trial team or lead clinician, to
•1.1. Medical thoracoscopy performed under conscious sedation
•1.2. Chest drain insertion
•1.3. Trial involvement
•2. Patient is unable to provide informed consent
•3. Thoracic imaging demonstrating septation or loculation to a degree whereby medical management alone would be inappropriate
•4. Maximum pleural fluid depth of =2cm on thoracic ultrasound
•5. Ongoing sepsis requiring haemodynamic support beyond basic fluid resuscitation
•6. Previous thoracic surgery on the side of the effusion
•7. Age <18
•8. Pregnancy or lactation
•9. Expected survival =3 months

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