NCT04586881已完成不适用
Catch me if You Can - the Individual Relationship Between Potential Ablation Targets From CARTOFINDER and Myocardial Fibrosis
Heart and Diabetes Center North-Rhine Westfalia1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2020年10月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- AF recurrence
研究概览
简要总结
Single center observational study to compare the relationship between atrial fibrosis and potential ablation targets from CARTOFINDER.
详细描述
A total number of 30 patients will undergo catheter Ablation for persistent AF. Pre-procedural cardiac MRI will be performed with late-gadolinium enhancement to visualize the individual amount and distribution of fibrosis in the right and left atrium. CARTOFINDER-guided mapping will be performed during the ablation procedure followed by AF ablation. The individual relationship between atrial fibrosis and potential ablation targets will be accessed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing their 1st AF ablation procedure for persistent atrial fibrillation (AF) as per recent Heart Rhythm Society (HRS) consensus document
- •Able to understand and willing to sign the Informed Consent Form.
- •Age ≥18 years.
排除标准
- •Contraindication for DE-MRI with a full dose of Gadolinium-based contrast agent.
- •Previous left atrial ablation or surgical procedure
- •Renal failure with CrCl <60 ml/min
- •Women currently pregnant, breastfeeding, or of childbearing age not currently taking or not willing to use a reliable form of contraception
- •Mental or physical inability to take part in the study
- •Uncontrolled hypertension
- •Morbid obesity (BMI > 35), or inability to be placed in MRI due to body mass.
结局指标
主要结局
AF recurrence
时间窗: 12 months
recurrence of atrial fibrillation after catheter ablation
次要结局
未报告次要终点
研究者
研究点 (1)
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