Eight-Week, Double-Blind, 3-Arm Parallel, Placebo-Controlled, Randomized Efficacy And Safety Trial Of Atomoxetine, Atomoxetine Plus Buspirone, And Placebo In Adults With Attention Deficit Hyperactivity Disorder

Pfizer12 个研究点分布在 1 个国家目标入组 241 人开始时间: 2004年11月最近更新: 2008年7月15日

适应症

试验速览

阶段: 2 期
状态: 已完成
发起方: Pfizer
入组人数: 241
试验地点: 12
主要终点: To assess the efficacy of Atomoxetine-Buspirone (ATX-BSP) vs placebo (PBO) and atomoxetine (ATX) monotherapy in adult patients with ADHD as measured by the mean change across 7 weeks in the Adult ADHD Investigator Symptom Rating Scale (AISRS) total score

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Determine if there is a difference in treatment response for adults with ADHD who are treated with Strattera versus those treated with a combination of Strattera and buspirone

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Double

入排标准

年龄范围: 18 Years 至 55 Years（Adult）
性别: All
接受健康志愿者: 否

入选标准

•Adults with ADHD

排除标准

•Other Axis I Psychiatric Disorders

结局指标

主要结局

To assess the efficacy of Atomoxetine-Buspirone (ATX-BSP) vs placebo (PBO) and atomoxetine (ATX) monotherapy in adult patients with ADHD as measured by the mean change across 7 weeks in the Adult ADHD Investigator Symptom Rating Scale (AISRS) total score

次要结局

To characterize the safety over 8 weeks of ATX-BSP as compared to PBO and ATX monotherapy. To assess the response rate for the 3 treatment groups based on AISRS and CGI scores.

研究者

发起方

Pfizer

申办方类型

Industry

研究点 (12)

Loading locations...

相似试验

已完成

4 期

Adult Study / OROS Methylphenidate Hydrochloride (HCL) (OROS MPH) in Adults With Attention Deficit Hyperactivity Disorder (ADHD)Attention Deficit Disorder With Hyperactivity

NCT00937040Ortho-McNeil Janssen Scientific Affairs, LLC357

已完成

3 期

Placebo-Controlled Multi-Centre Double-Blind Trial for Adults With Extended-Release Methylphenidate for ADHDAttention Deficit Hyperactivity Disorder

NCT00619840Medice Arzneimittel Pütter GmbH & Co KG363

已完成

3 期

Comparison of Lisdexamfetamine Dimesylate With Atomoxetine HCl in Attention-Deficit/Hyperactivity Disorder (ADHD) Subjects With an Inadequate Response to MethylphenidateAttention-Deficit/Hyperactivity Disorder

NCT01106430Shire267

已完成

2 期

A Controlled Study of Solriamfetol for Attention Deficit Hyperactivity Disorder (ADHD) in AdultsAttention Deficit Hyperactivity Disorder

NCT04839562Massachusetts General Hospital66

已完成

2 期

Investigating the Effect of Vortioxetine in Adult ADHD PatientsAttention Deficit Hyperactivity Disorder

NCT02327013H. Lundbeck A/S227