Estimation of Coronary Artery Hemodynamic Profiles Using Cineangiography Technique
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Coronary Clearance Frame Count
研究概览
简要总结
Study for developing techniques to evaluate coronary artery hemodynamic profiles by conventional angiography without more dedicated measuring devices.
详细描述
* Methods: Compare TIMI frame count, coronary clearance frame count in baseline/hyperemic coronary angiography with FFR, CFR, IMR and derive correlation, receiver-operating characteristic curve to find new tools estimating coronary hemodynamics by conventional angiography only.
A TIMI frame count is measured by counting the angiographic image cine frames during a head of radiocontrast column runs from the entry of left anterior descending artery (LAD) to the distal end.
A coronary clearance frame count is measured by counting the angiographic image cine frames during a tail of radiocontrast column runs from the entry of LAD to the distal end.
Baseline angiography is performed without any stimulation and hyperemic angiography is performed after intracoronary injection of adenosine 300ug or nicorandiol 2mg.
Inclusion criteria
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Hyperemic stimuli
Hyperemic stimuli of coronary flow by adenosine or nicorandil injection
干预措施: Hyperemic stimuli (Drug)
结局指标
主要结局
Coronary Clearance Frame Count
时间窗: Imediately after the procedure
frame count between the beginning and end of contrast column tail
TIMI frame count
时间窗: Imediately after the procedure
frame count between the beginning and end of contrast column head
Index of microcirculatory resistance
时间窗: During the procedure
derived from distal coronary pressure by transit time
次要结局
- Fractional flow reserve(During the procedure)
- Coronary flow reserve(During the procedure)