Confluence of Sleep, Circadian Rhythms, and the Menstrual Cycle on Injury Risk in Women
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Stride time
研究概览
简要总结
The investigators are conducting an observational trial examining young women over the course of 28 days in which we are monitoring movement, sleep, heart rate, oxygen saturation, gut physiology, light, and menstrual cycle. The inter- and independence of the cyclicity of these variables with each other, the circadian cycle, the menstrual cycle, and the sleep cycle will be tested.
详细描述
For 28 days, women will wear devices to capture: ambient light exposure, lower limb biomechanics, sleep, oxygen saturation, heart rate, temperature, and gut physiology.
Twice during the study, women will have saliva collected for 7 hours under dim light conditions in order to determine melatonin concentrations. During this 7-hour period, two blood draws for determination of proteomic profiles will also occur.
Daily urine samples will be tested for LH until the presence of the LH surge to help identify menstrual phase.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Regular menstrual cycle (21-35 days)
- •18-30 years old
排除标准
- •Neuromuscular or neurodegenerative disease
- •Gut disorders
- •circadian sleep disorders
- •prescription medications affecting sleep
- •recovering from physical injury
- •taking hormonal birth control
研究组 & 干预措施
Women
Young women with regular menstrual cycles
结局指标
主要结局
Stride time
时间窗: 28 days
Duration of each stride
次要结局
- Sleep(28 days)
研究者
Jamie Zeitzer
Professor
Stanford University