ITMCTR2100004302招募中1 期
Observation on Qingre Tongluo recipe in the treatment of difficult-to-treat rheumatoid arthritis with heat syndrome and its effect on drug resistance gene
Yunnan Hospital of Traditional Chinese Medicine/The First Affiliated Hospital of Yunnan University of traditional Chinese Medicine0 个研究点开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 年龄范围
- 18 至 70（—）
- 性别
- All
入选标准
- •1. Normal group
- •(1)Age 18 ~ 70 years, gender is not limited;
- •(2)denial of history of rheumatoid arthritis and history of immune diseases;
- •(3)no relevant history of severe acute and chronic diseases;
- •(4)informed consent, voluntary test.
- •2. The initial untreated group
- •(1)In line with the diagnostic criteria of RA Western medicine, and damp-heat obstruction syndrome of TCM diagnostic criteria;
- •(2)aged 18-70 years, gender;
- •(3)initial diagnosis without anti-RA drug treatment;
- •(4)the disease was active, DAS28 > 2.6.
- •3. Effective treatment group
- •(1)In line with RA western medicine diagnostic criteria, 1995 ACR20 treatment effective standard, and damp-heat obstruction syndrome of TCM diagnostic criteria;
- •(2)aged 18 – 70 years, gender unlimited;
- •(3)patients who were treated with DMARDs for more than half a year without using biological agents and hormones, were in remission, did not affect normal learning and work, and could take care of themselves;
- •(4)DAS28 <= 2.6;
- •(5)Sign informed consent, voluntary test.
- •4. Refractory group
- •(1)In line with RA western medicine diagnostic criteria, as well as damp-heat obstruction syndrome of TCM diagnostic criteria;
- •(2)aged 18 – 70 years, gender unlimited;
- •(3)patients who received regular application of two or more DMARDs for more than half a year were ineffective, and the disease was still active, unable to study and work normally, or even had difficulties in self-care;
- •(4)DAS28 > 3.2;
- •(5)patients whose symptoms did not meet the ACR20 remission standard;
- •(6)sign informed consent, voluntary test.
排除标准
- •(1) Patients who do not use the medicine according to the regulations cannot cooperate;
- •(2) Pregnant or lactating women;
- •(3) People who are currently infected with bacteria or viruses, or who are mentally or legally disabled; People with allergies or allergies to drugs such as methotrexate;
- •(4) Patients participating in other clinical trials;
- •(5) Patients with severe heart, liver and kidney dysfunction and accompanied by other malignant tumors;
- •(6) Those who have used biological agents and hormones within the last 3 months.
研究者
相似试验
尚未招募
2 期
Clinical observation of Xiaodian Tongluo Recipe in the treatment of recurrent skin allergic purpura in childreHenoch-Schonlein PurpuraITMCTR2100005247The First Affiliated Hospital of Henan University of traditional Chinese Medicine
招募中
1 期
Clinical study for the effect of Zhishi Tongjiang Granule on postoperative ileusITMCTR1900002363The Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine
尚未招募
1 期
Exploring the Mechanism of Fuzheng Tongluo Formula in Treating Gastric Cancer Precancerous Lesions Based on Neutrophil Extracellular TrapsITMCTR2024000192The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
招募中
1 期
Clinical study of Tonghua Liyan recipe in the treatment of laryngopharyngeal reflux with Qi stagnation and phlegm obstruction: A randomized, double-blind, placebo-controlled trialITMCTR2100004876Yueyang Integrated Traditional Chinese and Western Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine
尚未招募
1 期
The Effect of Bushen Jiedu Tongluo Decoction in the treatment of active rheumatoid arthritis: a randomized, double-blind, controlled clinical studyrheumatoid arthritisITMCTR2000003729Shuguang Hospital Affiliated to Shanghai University of traditional Chinese Medicine