Treating Late-Life Generalized Anxiety Disorder (GAD) in Primary Care
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 148
- 试验地点
- 2
- 主要终点
- Anxiety
研究概览
简要总结
The purpose of this study is to determine whether cognitive behavior therapy (CBT) is effective in the treatment of generalized anxiety disorder (GAD) in adults age 60 and older in a primary care setting.
详细描述
Generalized Anxiety Disorder (GAD) is one of the most common anxiety disorders among older adults. Anxiety in older adults is associated with decreased physical activity, poorer self-perceptions of health, decreased life satisfaction, and increased loneliness. Because many older adults with anxiety seek assistance in a medical setting, treatment has been primarily pharmacological. There is, however, limited evidence of the effectiveness of psychotropic medications. Given the potential difficulties in prescribing psychotropic medications in later life (e.g., increased adverse effects, potential drug interactions), psychosocial treatments may be important alternative or adjuncts.
The treatment phase of this study lasts 10 weeks, during which patients will be randomly assigned to either cognitive behavior therapy (CBT) or usual care. Follow-up will last 12 months after treatment completion, during which time patients will complete telephone assessments.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of Generalized Anxiety Disorder
排除标准
- •Active suicidal intent
- •Current psychosis
- •Current bipolar disorder
- •Substance abuse within past month
- •Cognitive impairment
结局指标
主要结局
Anxiety
时间窗: Baseline and 3, 6, 9, 12 and 15 months
次要结局
- Satisfaction with CBT and general health care(Baseline and 3, 6, 9, 12 and 15 months)
- Depression(Baseline and 3, 6, 9, 12 and 15 months)
- Quality of life inventory (QOLI)(Baseline and 3, 6, 9, 12 and 15 months)
- Sleep quality(Baseline and 3, 6, 9, 12 and 15 months)
- Use of alcohol and other substances(Baseline and 3, 6, 9, 12 and 15 months)
- Functional and health status(Baseline and 3, 6, 9, 12 and 15 months)
- Service utilization(Baseline and 3, 6, 9, 12 and 15 months)
研究者
Melinda Stanley
Professor
Baylor College of Medicine
