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临床试验/NCT00308724
NCT00308724已完成不适用

Treating Late-Life Generalized Anxiety Disorder (GAD) in Primary Care

Baylor College of Medicine2 个研究点 分布在 1 个国家目标入组 148 人开始时间: 2004年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
148
试验地点
2
主要终点
Anxiety

研究概览

简要总结

The purpose of this study is to determine whether cognitive behavior therapy (CBT) is effective in the treatment of generalized anxiety disorder (GAD) in adults age 60 and older in a primary care setting.

详细描述

Generalized Anxiety Disorder (GAD) is one of the most common anxiety disorders among older adults. Anxiety in older adults is associated with decreased physical activity, poorer self-perceptions of health, decreased life satisfaction, and increased loneliness. Because many older adults with anxiety seek assistance in a medical setting, treatment has been primarily pharmacological. There is, however, limited evidence of the effectiveness of psychotropic medications. Given the potential difficulties in prescribing psychotropic medications in later life (e.g., increased adverse effects, potential drug interactions), psychosocial treatments may be important alternative or adjuncts.

The treatment phase of this study lasts 10 weeks, during which patients will be randomly assigned to either cognitive behavior therapy (CBT) or usual care. Follow-up will last 12 months after treatment completion, during which time patients will complete telephone assessments.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Clinical diagnosis of Generalized Anxiety Disorder

排除标准

  • Active suicidal intent
  • Current psychosis
  • Current bipolar disorder
  • Substance abuse within past month
  • Cognitive impairment

结局指标

主要结局

Anxiety

时间窗: Baseline and 3, 6, 9, 12 and 15 months

次要结局

  • Satisfaction with CBT and general health care(Baseline and 3, 6, 9, 12 and 15 months)
  • Depression(Baseline and 3, 6, 9, 12 and 15 months)
  • Quality of life inventory (QOLI)(Baseline and 3, 6, 9, 12 and 15 months)
  • Sleep quality(Baseline and 3, 6, 9, 12 and 15 months)
  • Use of alcohol and other substances(Baseline and 3, 6, 9, 12 and 15 months)
  • Functional and health status(Baseline and 3, 6, 9, 12 and 15 months)
  • Service utilization(Baseline and 3, 6, 9, 12 and 15 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Melinda Stanley

Professor

Baylor College of Medicine

研究点 (2)

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