Peri Kasai Portoenterostomy Anchoring of the Jejunal Loop
试验速览
- 阶段
- 不适用
- 入组人数
- 26
- 试验地点
- 4
- 主要终点
- the total number of cholangitis
研究概览
简要总结
the study of the effect o the hanging of the jejunal loop to the peri KPE Glisson capsule on the rate of bile drainage and requirement of liver transplantation
详细描述
To evaluate the effect of anchoring jejunal loop to Glisson capsule of liver after completion of modified Kasai portoenterostomy (KPE) on the frequency of attacks of cholangitis and the overall incidence of native liver survival.
Methods: Retrospective study included 29 infants diagnosed as biliary atresia (BA). They were subjected to modified KPE. Two subgroups were present. Group A included 16 infants and had KPE. Group B included 13 infants and had the assumed modification. Wider dissection of fibrous portal plate was considered in both groups. After completion of KPE, the jejunal loop anchored to Glisson capsule of liver at porta hepatis in group B.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 4 Weeks 至 8 Weeks（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •infants with biliary atresia diagnosed and treated before 60th day of age
排除标准
- •infants older than 60 days
结局指标
主要结局
the total number of cholangitis
时间窗: two years
the total attacks of chollangitis
number of native liver survivors
时间窗: two years
the decrease of the need of liver transplantation in children with biliary atresia
次要结局
- early improvement of liver functions(6 months)
研究者
Mohammad Gharieb Mohammad Khirallah
Associate professor of pediatric surgery
Tanta University