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临床试验/NCT06562049
NCT06562049尚未招募不适用

Carpal Bone Erosion in Rheumatoid Arthritis :Diagnostic Value

Sohag University1 个研究点 分布在 1 个国家目标入组 110 人开始时间: 2024年8月15日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
110
试验地点
1
主要终点
bone erosion

研究概览

简要总结

Rheumatoid arthritis (RA) is a systemic inflammatory disease characterized by proliferative hyper vascularized synovitis which primarily affects synovial joints. Synovium of bursa; tendon sheaths; attachment sites of cartilage, ligament, and tendons to the bone; soft tissue; and bones can be mentioned among the other areas under influence of RA. Changes happen to be symmetrical and may present as fusiform soft tissue swelling, regional osteoporosis, marginal-central erosions, cartilage damage, joint destruction, narrowing of joint space and fibrous ankyloses. Wrist, metacarpophalangeal and metatarsophalangeal joints are the first sites to be affected .Over the past few years, an increasing number of rheumatologists have started to use US in the clinical setting of the early arthritis clinic. While US allows for an accurate and non-invasive multisite assessment of joint involvement in patients with RA, time for US examination is not infinite

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • RA patients fulfilled the 2010 American College of Rheumatoid Arthritis classification criteria.[8]
  • SLE patients fulfilled the 2019 ACR\EULAR classification criteria for SLE.[9]
  • Age above 18 years old.
  • Patient cooperative and can answer questions.
  • Patients who are able and willing to give written informed consent.

排除标准

  • Age below 18 years and above 60 years.
  • Uncooperative patients.
  • Patient not able and willing to give written informed consent.

结局指标

主要结局

bone erosion

时间窗: max 1 year

erosions in carpal bones and MCP 2,5 in both hands

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Abeer Abdelaal Aly

resident of Physical medicine, Rheumatology and Rehabilitation Department

Sohag University

研究点 (1)

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