Carpal Bone Erosion in Rheumatoid Arthritis :Diagnostic Value
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- bone erosion
研究概览
简要总结
Rheumatoid arthritis (RA) is a systemic inflammatory disease characterized by proliferative hyper vascularized synovitis which primarily affects synovial joints. Synovium of bursa; tendon sheaths; attachment sites of cartilage, ligament, and tendons to the bone; soft tissue; and bones can be mentioned among the other areas under influence of RA. Changes happen to be symmetrical and may present as fusiform soft tissue swelling, regional osteoporosis, marginal-central erosions, cartilage damage, joint destruction, narrowing of joint space and fibrous ankyloses. Wrist, metacarpophalangeal and metatarsophalangeal joints are the first sites to be affected .Over the past few years, an increasing number of rheumatologists have started to use US in the clinical setting of the early arthritis clinic. While US allows for an accurate and non-invasive multisite assessment of joint involvement in patients with RA, time for US examination is not infinite
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •RA patients fulfilled the 2010 American College of Rheumatoid Arthritis classification criteria.[8]
- •SLE patients fulfilled the 2019 ACR\EULAR classification criteria for SLE.[9]
- •Age above 18 years old.
- •Patient cooperative and can answer questions.
- •Patients who are able and willing to give written informed consent.
排除标准
- •Age below 18 years and above 60 years.
- •Uncooperative patients.
- •Patient not able and willing to give written informed consent.
结局指标
主要结局
bone erosion
时间窗: max 1 year
erosions in carpal bones and MCP 2,5 in both hands
次要结局
未报告次要终点
研究者
Abeer Abdelaal Aly
resident of Physical medicine, Rheumatology and Rehabilitation Department
Sohag University
