生产企业:IDEAYA Biosciences, Servier
IDE-196 is under investigation in clinical trial NCT03947385 (Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions).
IDE-196 is under investigation in clinical trial NCT03947385 (Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions).
Darovasertib is a first-in-class oral protein kinase C (PKC) inhibitor. It inhibits PKC isoforms downstream of the GNAQ/GNA11 activating mutations that drive uveal melanoma, thereby blocking constitutively activated PKC signaling.
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