Bufexamac
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Bufexamac is an NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
Bufexamac is an NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
The full mechanism of action is unclear. It is proposed that bufexamac acts similarly to other non-steroidal anti-inflammatory drugs to inhibit prostaglandin biosynthesis in vitro, via inhibiting cyclo-oxygenase (COX) enzymes . Systematically administered bufexamac may accumulate preferentially in the adrenal cortex of rats and may play a role in adrenal stimulation; however its topical anti-inflammatory action is likely to be independent of this effect .
Indicated for the treatment of various skin conditions, such as atopic eczema and other inflammatory dermatoses.
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