奥培米芬 (Osphena, Senshio)

概览

Ospemifene is a non-hormonal estrogen receptor modulator (SERM) used to treat moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause.

作用机制

Ospemifene is a next generation SERM (selective estrogen receptor modulator) that selectively binds to estrogen receptors and either stimulates or blocks estrogen's activity in different tissue types. It has an agonistic effect on the endometrium.

适应症

Ospemifene is indicated for the treatment of moderate to severe dyspareunia and vaginal dryness associated with menopause.

• Moderate Dyspareunia
• Moderate Vaginal dryness
• Severe Dyspareunia
• Severe Vaginal dryness