Benazepril
生产企业：Apotex inc etobicoke site, Aurobindo pharma ltd，另有 11 家
Benazepril is an ACE inhibitor prodrug used to treat hypertension.
Benazepril is an ACE inhibitor prodrug used to treat hypertension.
Benazeprilat, the active metabolite of Benazepril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in decreased plasma angiotensin II. As angiotensin II is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blood pressure and stimulation of baroreceptor reflex mechanisms, which leads to decreased vasopressor activity and to decreased aldosterone secretion.
Benazepril is indicated for the treatment of hypertension. It may be used alone or in combination with thiazide diuretics.
