未知生产厂商
Tallimustine is an alkylating agent previously investigated for it's antitumor activity but was stopped due to severe myelotoxicity.
Tallimustine is an alkylating agent previously investigated for it's antitumor activity but was stopped due to severe myelotoxicity.
Tallimustine binds to the minor groove of DNA while avoiding targets like glutathione. Currently, the mechanism of DNA minor groove binding agents is poorly understood. Though, they may act by directly inhibiting the interaction of protein and DNA.
Tallimustine was being investigated for its use in treating tumors. Derivatives of tallimustine with similar DNA binding ability and reduced myelotoxicity are being investigated for their antitumor activity.
