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Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen is a viable, bioengineered, allogeneic, cellularized scaffold product applied to deep thermal burns to aid in healing.
Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen is a viable, bioengineered, allogeneic, cellularized scaffold product applied to deep thermal burns to aid in healing.
Stratagraft consists of a murine collagen matrix with human keratinocytes and dermal fibroblasts embedded within. As these cells are viable and metabolically active, they secrete human growth factors and cytokines that help to heal the affected tissues. The Stratagraft cells are slowly replaced by the patient's own cells over time, which aids in wound closure and can help to eliminate or reduce the need for autologous skin grafting (i.e. autografting).
Stratagraft is an allogeneic cellularized scaffold product indicated for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (deep partial-thickness burns).
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