普环啶

概览

Procyclidine is an antispasmodic drug used to treat parkinsonism of various types and in the treatment of extrapyramidal symptoms.

作用机制

The mechanism of action is unknown. It is thought that Procyclidine acts by blocking central cholinergic receptors, and thus balancing cholinergic and dopaminergic activity in the basal ganglia. Many of its effects are due to its pharmacologic similarities with atropine. Procyclidine exerts an antispasmodic effect on smooth muscle, and may produce mydriasis and reduction in salivation.

适应症

For the treatment of all forms of Parkinson's Disease, as well as control of extrapyramidal reactions induced by antipsychotic agents.

• Drug Induced Parkinsonism
• Parkinsonism