辛可卡因 (Nupercainal, Proctol, Proctosedyl)

概览

Cinchocaine is an anesthetic used for local or regional anesthesia.

作用机制

Local anesthetics block both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions through sodium channel inhibition. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.

适应症

适用于硬膜外麻醉以及腰麻。也用于表面麻醉，较少用于浸润麻醉。

• Haemorrhoids
• Pruritis of the skin
• Pruritus Ani
• Skin Irritation