头孢呋辛 (Ceftin)

概览

Cefuroxime is a cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo.

作用机制

Cefuroxime, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefuroxime interferes with an autolysin inhibitor.

适应症

For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.

• Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
• Animal bite
• Bacterial Infections
• Bone and Joint Infections
• Impetigo
• Lower Respiratory Tract Infection (LRTI)
• Lyme Disease
• Maxillary Sinusitis
• Meningitis
• Neisseria Gonorrhoeae Infection
• Septicemia
• Skin and Subcutaneous Tissue Bacterial Infections