苯唑西林

概览

Oxacillin is a penicillin antibiotic used to treat a number of susceptible bacterial infections.

作用机制

By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Oxacillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Oxacillin interferes with an autolysin inhibitor.

适应症

Used in the treatment of resistant staphylococci infections.

• Catheter Related Infections
• Community Acquired Pneumonia (CAP)
• Infections caused by penicillinase-producing staphylococci
• Necrotizing Soft Tissue Infections
• Surgical Site Infections