氨苄西林 (Unasyn)

概览

Ampicillin is a penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.

作用机制

By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Ampicillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Ampicillin interferes with an autolysin inhibitor.

适应症

For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc

• Bacterial Infections
• Endocarditis
• Gastrointestinal Tract Infections
• Genitourinary tract infection
• Infection
• Infection caused by eikenella corrodens
• Listeria infection
• Meningitis, Bacterial
• Pertussis
• Respiratory Tract Infections (RTI)
• Salmonella
• Septicemia