Naratriptan
生产企业：Glaxosmithkline, Paddock laboratories inc，另有 3 家
Naratriptan is a 5-HT1B/1D receptor agonist used to treat migraines.
Naratriptan is a 5-HT1B/1D receptor agonist used to treat migraines.
Three distinct pharmacological actions have been implicated in the antimigraine effect of the triptans: (1) stimulation of presynaptic 5-HT1D receptors, which serves to inhibit both dural vasodilation and inflammation; (2) direct inhibition of trigeminal nuclei cell excitability via 5-HT1B/1D receptor agonism in the brainstem and (3) vasoconstriction of meningeal, dural, cerebral or pial vessels as a result of vascular 5-HT1B receptor agonism.
For the acute treatment of migraine attacks with or without aura in adults.
