Salcatonin(Salmon Calcitonin)
生产企业：Sanofi aventis us llc, Astrazeneca lp，另有 4 家
Salmon calcitonin is a synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease.
Salmon calcitonin is a synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease.
Calcitonin binds to the calcitonin receptor (found primarily in osteoclasts) which then enhances the production of vitamin D producing enzymes (25-hydroxyvitamine D-24-hydroxylase), leading to greater calcium retention and enhanced bone density. Binding of calcitonin to its receptor also activates adenylyl cyclase and the phosphatidyl-inositol-calcium pathway.
⑴绝经后骨质疏松症，老年骨质疏松症。 ⑵乳癌、肺或肾癌、骨髓瘤和其他恶性肿瘤骨转移所致的大量骨溶解和高钙血症。 ⑶各种骨代谢疾病所致的骨痛。 ⑷甲状旁腺功能亢进、缺乏活动或维生素D中毒（包括急性或慢性中毒）所致的变应性骨炎。 ⑸Paget病。 ⑹高钙血症和高钙血症危象。
