头孢克洛

概览

Cefaclor is a second generation cephalosporin used to treat a wide variety of infections in the body.

作用机制

Cefaclor, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins. It is possible that cefaclor interferes with an autolysin inhibitor.

适应症

For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.

• Acute Exacerbation of Chronic Bronchitis caused by Streptococcus Pneumoniae
• Acute Exacerbations of Chronic Bronchitis caused by Haemophilus Influenza
• Acute Exacerbations of Chronic Bronchitis caused by Moraxella catarrhalis
• Bacterial Infections
• Bacterial Urinary Tract Infections
• Lower respiratory tract infection bacterial
• Staphylococcal Skin Infections
• Streptococcal Pharyngitis
• Tonsillitis streptococcal
• Bacterial otitis media
• Streptococcus pyogenes skin infection
• Susceptible Bacterial Infections