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IPH-2101 (NN-1975), a fully human monoclonal antibody developed for patients with acute myeloid leukemia.
IPH-2101 (NN-1975), a fully human monoclonal antibody developed for patients with acute myeloid leukemia.
The therapeutic principle of IPH 2101 (NN 1975) is based on the activation of Natural Killer (NK) cells by a monoclonal antibody which blocks the NK’s KIR inhibitory receptors, thereby potentiating NK cells anti-cancer action.
Investigated for use/treatment in leukemia (myeloid) and multiple myeloma.