Ibutilide
生产企业：Pharmacia and upjohn co, Bioniche pharma usa llc，另有 1 家
Ibutilide is a class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion.
Ibutilide is a class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion.
Ibutilide is a 'pure' class III antiarrhythmic drug, used intravenously against atrial flutter and fibrillation. At a cellular level it exerts two main actions: induction of a persistent Na+ current sensitive to dihydropyridine Ca channel blockers and potent inhibition of the cardiac rapid delayed rectifier K current, by binding within potassium channel pores. In other words, Ibutilide binds to and alters the activity of hERG potassium channels, delayed inward rectifier potassium (IKr) channels and L-type (dihydropyridine sensitive) calcium channels
Indicated for the rapid conversion of atrial fibrillation or atrial flutter of recent onset to sinus rhythm.
共 2 项相关疾病
