卷曲霉素 (Capastat)

概览

Capreomycin is an aminoglycoside antibiotic used as an adjunct drug in tuberculosis.

作用机制

Little is known about capreomycin's exact mechanism of action, but it is thought to inhibit protein synthesis by binding to the 70S ribosomal unit. Capreomycin also binds to components in the bacterial cell which result in the production of abnormal proteins. These proteins are necessary for the bacteria's survival. Therefore the production of these abnormal proteins is ultimately fatal to the bacteria.

适应症

Used in the treatment of tuberculosis in combination with other drugs.

• Tuberculosis (TB)