Gazyvaro

Gazyvaro is a medicine used to treat adults with certain types of cancer affecting B cells (a type of white blood cell), called chronic lymphocytic leukaemia and follicular lymphoma, as well as the inflammatory kidney disease lupus nephritis. **Chronic lymphocytic leukaemia** Gazyvaro is used together with chlorambucil (a cancer medicine) in adults who have not been previously treated and have other medical conditions, and for whom the cancer medicine fludarabine is not recommended. **Follicular lymphoma** In patients with advanced follicular lymphoma who have not been previously treated, Gazyvaro is first given together with chemotherapy (other cancer medicines) and then continued on its own in those who benefit from the medicine. In patients with follicular lymphoma whose disease has not responded to treatment with rituximab, or whose cancer has progressed within 6 months after such treatment, Gazyvaro is given together with bendamustine and then continued on its own in those who benefit from the medicine. **Lupus nephritis** Gazyvaro is used together with mycophenolate mofetil in adults with active lupus nephritis, a condition in which the immune system (the body’s natural defences) attacks the kidneys, causing inflammation and kidney damage. The medicine is for people with active class III or IV lupus nephritis (with or without features of class V), which are severe forms of the condition. Gazyvaro contains the active substance obinutuzumab