Amversio is a medicine used to treat homocystinuria, an inherited disease where the amino acid homocysteine cannot be broken down and therefore builds up in the body. This causes a wide range of symptoms, including impaired vision, weak bones and circulatory problems. It is used with other treatments, such as vitamin B6 (pyridoxine), vitamin B12 (cobalamin), folate and a special diet. Amversio is a ‘generic medicine’. This means that Amversio contains the same active substance and works in the same way as a ‘reference medicine’ already authorised in the EU called Cystadane. Amversio contains the active substance betaine anhydrous.
Therapeutic Indication
### Therapeutic indication Amversio is indicated as adjunctive treatment of homocystinuria, involving deficiencies or defects in: - cystathionine beta-synthase (CBS), - 5,10 methylene tetrahydrofolate reductase (MTHFR), - cobalamin cofactor metabolism (cbl).
Therapeutic Area (MeSH)
ATC Code
A16AA06
ATC Item
betaine
Pharmacotherapeutic Group
Other alimentary tract and metabolism products
Active Substance (Summary)
INN / Common Names
| Substance | CAS | Monograph |
|---|---|---|
| betaine | N/A | 甜菜碱 |
EMA Name
Amversio
Medicine Name
Amversio
Aliases
N/A