Xtandi

<p>Xtandi is a cancer medicine used to treat men with prostate cancer. It can be used:</p><ul><li>together with hormone therapy (treatment to lower production of testosterone) when the cancer is metastatic (has spread to other parts of the body) and is hormone-sensitive (a cancer that depends on a hormone, such as testosterone, to grow);</li><li>for metastatic cancer that is castration-resistant (worsens despite treatment to lower production of testosterone or after surgical removal of the testes) and when either:<ul><li>treatment with docetaxel (a cancer medicine) has not worked or no longer works, or</li><li>hormone therapy has not worked, and the patient has either no symptoms or mild symptoms and does not yet require chemotherapy (another type of cancer treatment);</li></ul></li><li>for castration-resistant prostate cancer that is not metastatic (has not yet spread) but is at high risk of doing so;</li><li>on its own or together with hormone therapy for hormone-sensitive prostate cancer that is not metastatic if there are rapidly rising levels of prostate-specific antigen (PSA; a protein made by the prostate gland), indicating that the cancer may have returned, in men who cannot receive salvage radiotherapy (radiation treatment given after the cancer has not responded to other treatments).</li></ul><p>The medicine contains the active substance enzalutamide.</p>