- Approval Id
- a86d6f284f302140
- Drug Name
- CONJUPRI TABLETS 5MG
- Product Name
- CONJUPRI TABLETS 5MG
- Approval Number
- SIN17153P
- Approval Date
- 2024-12-26
- Registrant
- LOTUS INTERNATIONAL PTE. LTD.
- Licence Holder
- LOTUS INTERNATIONAL PTE. LTD.
- Drug Type
- Therapeutic
- Forensic Classification
- PRESCRIPTION ONLY MEDICINES
- Dosage Form
- TABLET
- Dosage
- <p>4.2 <u>Posology and method of administration</u></p>
<p>The usual initial dose is 2.5 mg levamlodipine once daily, which may be increased to a maximum dose of 5 mg depending on the individual patient’s response.</p>
<p>No dose adjustment of levamlodipine is required upon concomitant administration of thiazide diuretics, beta-blockers, and ACE inhibitors.</p>
<p><em>Use in the Elderly</em></p>
<p>Normal dosage regimens are recommended. Amlodipine, used at similar doses in the elderly or younger patients, is equally well-tolerated.</p>
<p><em>Use in Children</em></p>
<p>Safety and effectiveness of levamlodipine in children have not been established.</p>
<p><em>Use in Patients with Impaired Hepatic Function</em></p>
<p>See section 4.4. Special warnings and precautions for use – <em>please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information</em>.</p>
<p><em>Use in Patients with Renal Failure</em></p>
<p>Levamlodipine may be used at normal doses in patients with renal failure. Changes in amlodipine plasma concentrations are not correlated with the degree of renal impairment.</p>
<p>Amlodipine is not dialyzable.</p>
- Route Of Administration
- ORAL
- Indication Info
- <p>4.1 <u>Therapeutic indications</u></p>
<p><strong>Hypertension</strong></p>
<p>Levamlodipine is indicated for the first-line treatment of hypertension and can be used as the sole agent to control blood pressure in the majority of patients. Patients not adequately controlled on a single antihypertensive agent may benefit from the addition of levamlodipine, which has been used in combination with a thiazide diuretic, alpha blockers, beta adrenoceptor blocking agent, or an angiotensin-converting enzyme (ACE) inhibitor.</p>
- Contraindications
- <p>4.3 <u>Contraindications</u></p>
<p>Levamlodipine is contraindicated in patients with a known hypersensitivity to dihydropyridines* or any of the inert ingredients.</p>
<p>* Amlodipine is a dihydropyridine calcium channel blocker.</p>
- Atc Code
- C08CA17
- Pharma Manufacturer Name
- LOTUS INTERNATIONAL PTE. LTD.
