- Approval Id
- c5cc4188153310e1
- Drug Name
- JAMP SODIUM POLYSTYRENE SULFONATE POWDER FOR SUSPENSION 1G/G
- Product Name
- JAMP SODIUM POLYSTYRENE SULFONATE POWDER FOR SUSPENSION 1G/G
- Approval Number
- SIN16808P
- Approval Date
- 2023-06-14
- Registrant
- GOLDPLUS UNIVERSAL PTE LTD
- Licence Holder
- GOLDPLUS UNIVERSAL PTE LTD
- Drug Type
- Therapeutic
- Forensic Classification
- Prescription Only
- Dosage Form
- POWDER, FOR SUSPENSION
- Dosage
- <p><strong>DOSAGE</strong><br>
JAMP Sodium Polystyrene Sulfonate can be given by mouth or in the rectum.</p>
<p>The amount of JAMP Sodium Polystyrene Sulfonate you need to take will depend upon the amount of potassium in your blood.</p>
<p>Once the mixture has been prepared, it should be used straight away. If it needs to be stored, it should be stored for no longer than 24 hours. Do not heat JAMP Sodium Polystyrene Sulfonate.</p>
<p><strong><u>Oral Dosing</u></strong><br>
When taken by mouth, JAMP Sodium Polystyrene Sulfonate should be taken at least 3 hours before or 3 hours after other oral medications. For patients with gastroparesis (a condition preventing your stomach from emptying properly), a 6-hour separation should be considered. Consult your health care provider for recommendations (see WARNINGS AND PRECAUTIONS and DRUG INTERACTIONS – <em>please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information</em>).</p>
<p>JAMP Sodium Polystyrene Sulfonate powder is usually given by mouth mixed in a small amount of water. It can also be mixed with sweetened liquid. Do NOT mix JAMP Sodium Polystyrene Sulfonate with orange juice or fruit juice which contains potassium.</p>
<p>JAMP Sodium Polystyrene Sulfonate is a powder. Be careful not to inhale it accidentally. Breathing in the powder may cause coughing and shortness of breath.</p>
<p>Your doctor will regularly check the potassium, calcium and magnesium levels in your blood. The doctor may change the dose or stop the JAMP Sodium Polystyrene Sulfonate depending on what the results of these blood tests are.</p>
<p><strong><em>Adults, including the elderly:</em></strong><br>
15 g one to four times daily as indicated above.</p>
<p><strong><em>Children:</em></strong><br>
You should follow the dosing recommended by your doctor. For children, JAMP Sodium Polystyrene Sulfonate is preferably given with water (NOT a fruit juice because of the high potassium content) or a little jam or honey.</p>
<p><strong><em>Newborn babies (neonates):</em></strong><br>
JAMP Sodium Polystyrene Sulfonate should not be given by mouth.</p>
<p><strong><u>Rectal Dosing</u></strong><br>
The enema is usually given by a doctor or nurse.</p>
<p><em><strong>Adults:</strong></em><br>
The enema should be prepared by the pharmacist or the nurse. 30 to 45g should be administered once or twice daily at interval of six hours. The enema should be retained in the rectum for as long as possible. Afterwards, the colon needs to be washed out to remove JAMP Sodium Polystyrene Sulfonate.</p>
<p><em><strong>Children and infants:</strong></em><br>
The enema should be prepared by the pharmacist or the nurse. The enema should be retained in the rectum for as long as possible. Afterwards, the colon needs to be washed out to remove JAMP Sodium Polystyrene Sulfonate.</p>
<p>The resin may also be given, although with less effective results, in a daily enema consisting (for adults) of 30 to 45 g once or twice daily at 6-hour intervals. Each dose is administered as a warm emulsion (at body temperature) in 150 to 200 mL of aqueous vehicle (such as plain water, 10% dextrose in water, or equal parts of water and 2% methylcellulose suspension). The emulsion should be agitated gently during administration. The enema should be retained for as long as possible and followed by a cleansing enema. Use of sorbitol in enemas in contraindicated. After the initial cleansing enema, a soft, large size (French 28) rubber tube is inserted into the rectum for a distance of about 20 cm, with the tip well into the sigmoid colon, and taped in place. The resin is then suspended in the appropriate amount of water or 10% dextrose at body temperature and introduced by gravity, while the particles are kept in suspension by stirring.</p>
<p>The suspension is flushed with 50 or 100 mL of saline solution, following which the tube is clamped and left in place. If back leakage occurs, the hips are elevated on pillows or a knee-chest position is taken temporarily.<br>
A somewhat thicker suspension may be used, but care should be taken that no paste is formed, because the latter has a greatly reduced exchange surface and will be particularly ineffective, if deposited in the rectal ampulla. The suspension is kept in the sigmoid colon for several hours, if possible. Then, the colon is irrigated, with a nonsodium containing solution at body temperature in order to remove the resin. Two quarts of flushing solution may be necessary. The returns are drained constantly through a Y tube connection.<br>
The intensity and duration of therapy depends upon the severity and resistance of hyperkalemia.</p>
<p>The resin should not be heated as it may alter its exchange properties.</p>
- Route Of Administration
- ORAL, RECTAL
- Indication Info
- <p><strong>INDICATION</strong><br>
JAMP Sodium Polystyrene Sulfonate is indicated for the treatment of hyperkalemia.</p>
- Contraindications
- <p><strong>CONTRAINDICATIONS</strong></p>
<p>JAMP Sodium Polystyrene Sulfonate should not be administered to patients with the following conditions:</p>
<ul>
<li>serum potassium <5 mmol / L</li>
<li>history of hypersensitivity to polystyrene sulfonate resins</li>
<li>obstructive bowel disease</li>
</ul>
<p>JAMP Sodium Polystyrene Sulfonate should not be administered <em><strong>orally</strong></em> to neonates or in neonates with reduced gut motility (postoperatively or drug induced).</p>
- Atc Code
- V03AE01
- Atc Item Name
- polystyrene sulfonate
- Pharma Manufacturer Name
- GOLDPLUS UNIVERSAL PTE LTD
