卢非酰胺 (Banzel, Inovelon)

Rufinamide

未知生产厂商

Rufinamide is an antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS).

生成 AI 研报

医学正文保留数据源原文，避免将未经专业审核的机器翻译呈现为临床事实。

概览

Rufinamide is an antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS).

作用机制

Rufinamide is a triazole derivative antiepileptic that prolongs the inactive state of voltage gated sodium channels thus stabilizing membranes, ultimately blocking the spread of partial seizure activity.

适应症

治疗4岁以上及成人Lennox-Gastaut症候群的癫痫症。

专利

每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。

USE OF CANNABINOIDS IN THE TREATMENT OF SEIZURES AS ASSOCIATED WITH LENNOX-GASTAUT SYNDROME
US 2021169824 A1申请人: GW RES LTD优先权: 2017
CN
EP
US
WO
5 件公开
Polymorph of 1-(2,6-difluorobenzyl)-1h-1,2,3-triazole-carboxamide
EP 2727914 A1申请人: LESVI LABORATORIOS SL优先权: 2010
EP
US
3 件公开
Process for the purification of rufinamide
US 8461190 B2申请人: ALLEGRINI PIETRO优先权: 2011
EP
US
3 件公开
Pharmaceutical composition comprising (1r,4r)-6-fluoro-N, N-dimethyl-4-phenyl-4,9-dihydro-3H-spiro[cyclohexane-1,1-pyrano[3,4,b]indol]-4-amine and an anticonvulsant
US 9345689 B2申请人: GRUENENTHAL GMBH优先权: 2013
CN
US
3 件公开
Rufinamide for use in the treatment of myotonia
US 12023322 B2申请人: UNIV AARHUS优先权: 2015
CN
US
3 件公开
CRYSTALLINE FORMS OF RUFINAMIDE
US 2011034523 A1申请人: DIPHARMA FRANCIS SRL优先权: 2009
EP
US
2 件公开
Process for the preparation of rufinamide
US 8183269 B2申请人: KANKAN RAJENDRA NARAYANRAO优先权: 2008
US
2 件公开
Method for the preparation of rufinamide
US 8198459 B2申请人: ATTOLINO EMANUELE优先权: 2009
US
2 件公开
Process for preparation of rufinamide
- US 8871945 B2
  申请人: DAVULURI RAMAMOHAN RAO优先权: 2010
  US
  2 件公开
- US 2014357871 A1
  申请人: LUPIN LTD优先权: 2012
  US
RUFINAMIDE SOLID DISPERSION
US 2015182458 A1申请人: HETERO RESEARCH FOUNDATION优先权: 2012
US
2 件公开

药物

卢非酰胺 (Banzel, Inovelon)

概览

作用机制

适应症

相关疾病

专利

Process for preparation of rufinamide