Molindone

概览

Molindone is an antipsychotic used to treat schizophrenia.

作用机制

The exact mechanism has not been established, however, based on electroencephalogram (EEG) studies, molindone is thought to act by occupying (antagonizing) dopamine (D2) receptor sites in the reticular limbic systems in the brain, thus decreasing dopamine activity. Decreased dopamine activity results in decreased physiological effects normally induced by excessive dopamine stimulation, such as those typically seen in manifestations of psychotic disorders.

适应症

Molindone is used for the management of the manifestations of psychotic disorders.

• Schizophrenia