枸橼酸钾 (Cytra-K, Urocit-K)

概览

Potassium citrate is an agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones.

作用机制

After oral administration of potassium citrate, its metabolism yields alkaline load. Potassium Citrate therapy appears to increase urinary citrate mainly by modifying the renal handling of citrate, rather than by increasing the filtered load of citrate. In addition to raising urinary pH and citrate, Potassium Citrate increases urinary potassium by approximately the amount contained in the medication. In some patients, Potassium Citrate causes a transient reduction in urinary calcium.

适应症

For the management of renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones.

• Bowel preparation therapy
• Constipation
• Hypocitraturic calcium oxalate nephrolithiasis
• Kidney Stones
• Metabolic Acidosis
• Renal tubular acidosis
• Uremia
• Uric Acid Nephrolithiasis
• Chronic metabolic acidosis