Dacarbazine
生产企业：Abraxis pharmaceutical products, App pharmaceuticals llc，另有 4 家
Dacarbazine is an antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
Dacarbazine is an antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
The mechanism of action is not known, but appears to exert cytotoxic effects via its action as an alkylating agent. Other theories include DNA synthesis inhibition by its action as a purine analog, and interaction with SH groups. Dacarbazine is not cell cycle-phase specific.
For the treatment of metastatic malignant melanoma. In addition, dacarbazine is also indicated for Hodgkin's disease as a secondary-line therapy when used in combination with other antineoplastic agents.
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