布罗利尤单抗 (Siliq, Kyntheum)

概览

Brodalumab is a monoclonal antibody used to treat moderate to severe plaque psoriasis.

作用机制

Brodalumab binds with high affinity to interleukin (IL)-17 receptor A, thereby inhibiting several pro-inflammatory cytokines from the IL-17 family.

适应症

Brodalumab has been approved for the treatment of psoriasis vulgaris, psoriatic arthritis, pustular psoriasis and psoriatic erythroderma.

• Severe Plaque psoriasis
• Moderate Plaque psoriasis