麦迪霉素

概览

Midecamycin is a macrolide antibiotic used to treat a variety of infections caused by susceptible bacteria.

作用机制

Midecamycin, as part of the macrolides, act by inhibiting bacterial protein synthesis. More specifically, midecamycin inhibits bacterial growth by targetting the 50S ribosomal subunit preventing peptide bond formation and translocation during protein synthesis. The presence of mutations in the 50S RNA can prevent midecamycin binding. Midecamycin is a broad spectrum antibiotic and thus, it can interact with different bacteria.

适应症

Midecamycin was used for the treatment of infections in the oral cavity, upper and lower respiratory tracts and skin and soft tissue infections. The alone use of midecamycin was mainly used in Europe or Japan.

• Abscess bacterial
• Bacterial Pneumonia
• Bronchitis bacterial
• Laryngitis bacterial
• Otitis Media (OM)
• Pharyngitis bacterial
• Tonsillitis bacterial