卡泊芬净 (Cancidas, Cancidas (previously Caspofungin MSD), Caspofungin Accord)

概览

Caspofungin is an echinocandin used to treat a variety of fungal infections.

作用机制

Caspofungin inhibits the synthesis of beta-(1,3)-D-glucan, an essential component of the cell wall of Aspergillus species and Candida species. beta-(1,3)-D-glucan is not present in mammalian cells. The primary target is beta-(1,3)-glucan synthase.

适应症

For the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies.

• Abscess, Intra-Abdominal
• Candidemia
• Esophageal Candidiasis
• Fungal Infections
• Invasive Aspergillosis
• Oropharyngeal Candidiasis
• Peritonitis
• Pleural space infections