Methysergide
生产企业：Novartis pharmaceuticals corp
Methysergide is an ergot alkaloid used for the prophylaxis of migraine and cluster headaches.
Methysergide is an ergot alkaloid used for the prophylaxis of migraine and cluster headaches.
Methysergide is serotonin antagonists acts on central nervous system (CNS), which directly stimulates the smooth muscle leading to vasoconstriction. Some alpha-adrenergic blocking activity has been reported. Suggestions have been made by investigators as to the mechanism whereby Methysergide produces its clinical effects, but this has not been finally established, although it may be related to the antiserotonin effect.
适用于预防严重的或反复发作的偏头痛。对偏头痛急性发作无效。
