DOMINA Tablet Compression Platform Wins The Medicine Maker Innovation Awards 2025 Grand Prize
核心洞察
IMA Active (搜索)'s DOMINA (搜索) modular tablet compression platform has been named Grand Winner of The Medicine Maker Innovation Awards 2025, recognizing its contributions to Pharma 4.0 manufacturing.
The platform features a modular, plug-and-play architecture enabling manufacturers to configure setups for different powders, formulations, and transitions between mono- and bilayer tablet production.
Key technical innovations include the patented Dynamicam filling system, Preforma compaction cam for improved de-aeration, and machine learning capabilities integrated with the Kortex MAX HMI system.
Following another strong year for pharmaceutical development and manufacturing technologies, readers of The Medicine Maker have selected DOMINA (搜索) from IMA Active (搜索) as the Grand Winner of The Innovation Awards 2025. The modular technological platform, designed for Pharma 4.0 manufacturing, reimagines tablet compression at a time when the industry faces mounting demands around flexibility, sustainability, data integrity, and time-to-market.
DOMINA (搜索) allows manufacturers to configure the ideal setup for different powders, formulations, and tablet types — including seamless transitions between mono- and bilayer production. Its plug-and-play architecture is supported by a suite of process-focused innovations that address persistent challenges in oral solid dose manufacturing.
A Platform Built for Flexibility
The concept for DOMINA (搜索) emerged from what Luca Cavazzini, Sales & Marketing Director at IMA Active (搜索), described as "a simple but fundamental question: how can we rethink tablet compression to better respond to a fast-changing industry?"
"Traditional machine concepts were reaching their limits in terms of flexibility and scalability," Cavazzini explained. "The idea was to create not just a new tablet press, but a platform — a modular system where functional blocks could be reconfigured according to production needs."
This vision led to what the company calls a "new technological language" in tableting, combining mechanical excellence with digital intelligence to enable manufacturers to move from fixed configurations to adaptable production systems.
Key Technical Innovations
Among DOMINA (搜索)'s standout features is the patented Dynamicam filling system, which enables highly precise and consistent die filling even at high speeds, improving weight uniformity and overall product quality. The platform also incorporates single-motorized paddle feeding solutions and Preforma, a specialized compaction cam designed to enhance powder de-aeration and reduce the risk of lamination and capping.
"On the compression side, we focused on better control of how the powder behaves throughout the compaction cycle," Cavazzini noted. "The introduction of an additional compaction step with the Preforma compaction cam allows for a more gradual densification of the powder bed, improving air removal and stress distribution before main compression."
The platform integrates advanced automation, adaptive diagnostics, machine learning capabilities, and the Kortex MAX HMI system, offering manufacturers a flexible, data-driven platform for oral solid dose production.
Addressing Industry Challenges
Pharmaceutical manufacturers today are navigating a convergence of challenges that extend beyond production performance. According to IMA Active (搜索), sustainability has become a strategic priority, requiring energy-efficient technologies, reduced waste, and more responsible use of resources. Simultaneously, regulatory expectations around data integrity and compliance are increasing, while supply chain volatility pushes companies toward more flexible and resilient production models.
"The growing complexity of processes, combined with the need to reduce time-to-market, calls for technologies that are not only highly efficient, but also adaptable, easy to operate, and capable of integrating seamlessly into digital ecosystems," Cavazzini said.
The Role of Digitalization
Digitalization serves as a key enabler for the future of tablet production, with technologies such as real-time monitoring, predictive analytics, and advanced algorithms allowing machines to continuously adapt and optimize performance. This leads to more stable processes, reduced waste, and better data-driven decision-making.
"The challenge moving forward will be ensuring data integration, regulatory compliance, and the development of the right skills to fully leverage these technologies," Cavazzini added.
Industry Response and Future Outlook
The response from the pharmaceutical industry has been strong, particularly from manufacturers working with complex or sensitive formulations. There is growing interest in technologies that can improve process robustness and reduce variability, especially under high-speed production conditions.
For manufacturers, DOMINA (搜索) enables more efficient, flexible, and reliable production, reducing downtime, optimizing resource usage, and accelerating time-to-market. For patients, innovation at the manufacturing level translates into faster access to therapies and improved reliability of treatments.
Looking ahead, IMA Active (搜索) anticipates further developments in continuous manufacturing, deeper integration of AI and digital twins, and even more flexible and sustainable production models. "The real goal is to create a balance between technological sophistication and human-centered design," Cavazzini concluded.
Nominations for The Medicine Maker Innovation Awards 2026 will open on July 31.