Enterome Strengthens Board with BeiGene's Former CMO as OncoMimics Platform Shows Promise in Cancer Trials
核心洞察
Enterome has appointed Dr. Mehrdad Mobasher, former Chief Medical Officer at BeiGene (搜索) and current IFLI (搜索) Executive Partner, to its Board of Directors to strengthen leadership in developing OncoMimics (搜索) immunotherapies.
The company's lead candidate EO2463 has shown positive Phase 2 interim data in low tumor-burden follicular lymphoma (搜索) and received FDA Fast Track designation for the watch and wait setting.
IFLI (搜索), a key investor that contributed up to $9 million in Enterome's $19 million funding round, continues to support the development of OncoMimics (搜索) therapies targeting B-cell lymphomas.
Enterome SA has appointed Dr. Mehrdad Mobasher, a prominent hematologist-oncologist and former Chief Medical Officer at BeiGene (搜索), to its Board of Directors as the clinical-stage company advances its OncoMimics (搜索) immunotherapy platform through Phase 2 trials. The appointment strengthens ties with the Institute for Follicular Lymphoma (搜索) Innovation (IFLI (搜索)), which invested up to $9 million in Enterome's recent funding round and where Dr. Mobasher serves as Executive Partner.
Strategic Leadership Addition
Dr. Mobasher brings over 15 years of leadership experience in global drug development and commercialization to Enterome's board. Most recently serving as Chief Medical Officer at BeiGene (搜索), he led the hematology portfolio and global launch of zanubrutinib in chronic lymphocytic leukemia (搜索) and follicular lymphoma (搜索). His previous roles include Global Head of Oncology Development at Zai Lab, Chief Medical Officer at Corvus Pharmaceuticals, and Group Medical Director at Genentech, where he spearheaded the development and launch of landmark oncology programs including venetoclax and obinutuzumab.
"IFLI (搜索)'s highly collaborative support for the development of our OncoMimics (搜索) in vivo immune therapies targeting follicular lymphoma (搜索) and other forms of B-cell lymphoma (搜索) has been transformative for Enterome. Dr. Mobasher joining our board further strengthens IFLI's invaluable support," said Pierre Belichard, CEO at Enterome.
OncoMimics Platform Advances
Enterome's OncoMimics (搜索) represent a new class of off-the-shelf, multi-targeted in vivo immune therapies designed to induce rapid and potent expansion of memory T-cells (搜索) to fight cancer. The company's pioneering approach utilizes a bacterial Mimicry drug discovery platform that identifies OncoMimics with high similarity to tumor-associated antigens (搜索) based on big-data insights from millions of gut bacterial proteins.
The company has reported encouraging clinical results across multiple cancer types. In December, Enterome presented positive updated Phase 2 interim data from two cohorts of patients with low tumor-burden follicular lymphoma (搜索) for its lead OncoMimics (搜索) immunotherapy EO2463. The therapy also secured FDA Fast Track designation for the watch and wait setting in follicular lymphoma in October.
Clinical Pipeline Progress
Beyond follicular lymphoma (搜索), Enterome has demonstrated the versatility of its OncoMimics (搜索) platform across different cancer types. The company has provided positive data updates for EO4010 in metastatic colorectal cancer (搜索) and for EO2401 in glioblastoma (搜索). All three of the company's most advanced product candidates have shown positive early data in Phase 2 clinical development, supporting the novel OncoMimics modality.
"Enterome has generated promising clinical data in B-cell non-Hodgkin lymphomas (搜索), including follicular lymphoma (搜索), as well as in selected solid tumors through an entirely new immunotherapy approach. I'm excited to join the Board and work with the leadership team to help translate this innovative science into meaningful outcomes for patients," said Dr. Mobasher.
Strategic Partnership with IFLI
The Institute for Follicular Lymphoma (搜索) Innovation became an Enterome shareholder when it invested up to $9 million in a $19 million private funding round in June 2025. IFLI (搜索) is a global non-profit foundation dedicated to accelerating the development of innovative treatment options for patients with follicular lymphoma. The foundation supports cutting-edge research and technology development, deploying its budget across research funding, project-based partnerships, and venture philanthropic investments.
Dr. Mobasher was named Executive Partner at IFLI (搜索) in October 2025, positioning him to bridge the strategic relationship between the foundation and Enterome as the company advances its OncoMimics (搜索) therapies targeting B-cell lymphomas.