Concept Medical, Inc.

SirPAD Trial Demonstrates Superior Efficacy of Sirolimus-Coated Balloons in Peripheral Artery Disease Treatment

- The SirPAD trial, the world's largest randomized controlled study of sirolimus-coated balloons for peripheral artery disease, enrolled 1,252 patients and demonstrated superior outcomes compared to uncoated balloon angioplasty. - MagicTouch PTA sirolimus-coated balloons reduced major adverse limb events to 8.8% versus 15% with uncoated balloons at one year, showing a risk difference of -4.9%. - The academic all-comers trial included nearly 50% of patients with acute or chronic limb-threatening ischemia, providing robust clinical evidence for hard outcomes. - Results were simultaneously published in the New England Journal of Medicine and presented at ACC 2026, marking a potential turning point for PAD treatment guidelines.