相关临床试验
101
39 进行中
药物批准
0
批准总数
监管机构
0
监管机构数
成立时间
1991
进行中（未招募）
6
5.9%
已完成
30
29.7%
尚未招募
33
32.7%
招募中
27
26.7%
终止
3
3.0%
撤回
2
2.0%
暂无批准数据
- Western Australia's Cook Labor Government and The Hospital Research Foundation Group have awarded $775,000 to 15 precision medicine research projects across the state. - Four researchers received Tier One grants of $125,000 over two years, while 11 projects received Tier Two grants of $25,000 over one year. - Funded work targets cancer, dementia, cardiovascular disease, stroke and mental health, including a precision nasal spray for Alzheimer's disease. - The competitive grant round marks the third major collaboration between The Hospital Research Foundation Group and the FHRI Fund in the past 12 months.
- A new study from Edith Cowan University reveals that sleep patterns can alter how aquaporin-4 (AQP4) gene variants influence gray matter loss and cognitive decline associated with Alzheimer's disease. - Individuals carrying certain AQP4 variants showed faster gray matter loss when reporting shorter sleep, while others experienced structural brain changes linked to longer sleep onset times. - The findings suggest that poor sleep does not affect Alzheimer's-related brain changes through a single pathway, and the same genetic variant can appear protective or detrimental depending on sleep habits. - Researchers call for genetically informed clinical trials to test whether tailored sleep interventions can reduce risk in people with specific AQP4 variants, advancing a precision health approach to Alzheimer's prevention.
- Physical fitness components including muscle strength and cardiorespiratory fitness were found to reduce cancer mortality by 31-46%, according to a comprehensive review of 42 studies involving nearly 47,000 patients. - Pre-diagnosis exercise provides substantial protection against cancer progression, with moderate to vigorous physical activity reducing progression risk by 27% and death risk by 47% compared to sedentary individuals. - Benefits extend to patients with advanced-stage cancers, suggesting exercise interventions could be incorporated into standard cancer treatment protocols to improve survival outcomes.
- Australian researchers demonstrate success in the largest internet-based cognitive decline prevention trial, showing improved cognition through lifestyle modifications in adults aged 55-77. - The Maintain Your Brain study, tracking over 6,000 participants, achieved cognitive improvements equivalent to delaying dementia onset by one year through targeted interventions in exercise, diet, and mental health. - Online coaching program successfully improved participants' cognitive scores, physical activity levels, dietary habits, and mental health outcomes, with greater engagement correlating to better results.
