相关临床试验
78
7 进行中
药物批准
0
批准总数
监管机构
0
监管机构数
成立时间
1949
已完成
47
60.3%
尚未招募
7
9.0%
招募中
23
29.5%
暂停
1
1.3%
暂无批准数据
- Japanese researchers developed a silver nanoparticle-based method that improves DNA assembly efficiency by two to five times compared with standard restriction enzyme approaches. - PEG-coated silver nanoparticles achieved over 91% DNA cleaving efficiency at 50°C within one to two hours, with DNA recovery rates rising from 14% to 98%. - The method successfully produced 8-base and 18-base sticky ends, with 18-base overhangs reaching 44% joining efficiency versus 8% for conventional 4-base overhangs. - The technique was validated in human HeLa cells, where assembled DNA encoding green fluorescent protein (GFP) was successfully expressed.
- Fujitsu and Tokai National Higher Education and Research System (THERS) have completed successful field trials using generative AI to structure clinical data, achieving approximately 90% accuracy with 1,800 breast surgery patient records. - The AI-powered approach identified 42 potential clinical trial candidates with 27 being actually eligible, potentially reducing patient selection time by approximately one-third and accelerating clinical research processes. - This initiative directly addresses Japan's "drug loss" problem—the lack of availability of drugs used overseas due to stringent local approval requirements—by streamlining clinical trials and improving real-world data utilization.
