HYPHENS PHARMA PTE. LTD.

**4.1 Therapeutic indications** Temporary improvement in the appearance of moderate to severe glabellar lines (vertical lines between the eyebrows) associated with corrugator muscle and/or procerus muscle activities, in adults below 65 years of age.

**4.1. Therapeutic indications** Mucolytic agent for use in adults with acute and chronic respiratory disorders (including chronic obstructive pulmonary disease, acute exacerbations of chronic obstructive pulmonary disease, rhinosinusitis, pharingolaryngotracheitis, acute and chronic bronchitis) associated with excessive mucus production.

**4.1 Therapeutic indications** Indicated for the prevention and treatment of vitamin D deficiency. As an adjunct to specific therapy for osteoporosis in patients with vitamin D deficiency or at risk of vitamin D insufficiency.

**4.1 Therapeutic indications** Rupafin 1 mg/ml oral solution is indicated for the symptomatic treatment of: - Allergic rhinitis (including persistent allergic rhinitis) in children aged 2 to 11 years (see section 5.1 – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_). - Urticaria in children aged 2 to 11 years (see section 5.1 – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_).

**4.1 Therapeutic indications** Pravafen is indicated as an adjunct to diet to reduce triglyceride (TG) and increase HDL-C in high coronary heart disease (CHD) -risk adult patients with mixed dyslipidemia whose LDL-C levels are adequately controlled while on a treatment with pravastatin 40 mg monotherapy. No incremental benefit of Pravafen on cardiovascular morbidity and mortality has been established over and above that demonstrated for statin monotherapy.

**4.1 Therapeutic indications** Emergency contraception within 120 hours (5 days) of unprotected sexual intercourse or contraceptive failure.

**THERAPEUTIC INDICATIONS** 1. Prophylaxis and treatment of bronchoconstriction in patients with asthma as an add-on to inhaled glucocorticosteroid treatment. 2. Prophylaxis of bronchospasm induced by inhaled allergens, cold air, or exercise.